Download PDF by Robert B. McComb: Alkaline Phosphatase

By Robert B. McComb

ISBN-10: 1461329701

ISBN-13: 9781461329701

ISBN-10: 1461329728

ISBN-13: 9781461329725

There will be doubtless that alkaline phosphatase is likely one of the so much commonly in­ vestigated of all enzymes. This has resulted from the ubiquity of its distribution, and from the convenience and sensitivity with which its job will be measured. regrettably, those wide-ranging yet frequently superficial experimental reviews were up by way of in depth and systematic investigations in just a couple of constrained parts of the biochemistry and chemical pathology of alkaline phosphatase. the end result has been the buildup of a systematic literature of intimidating proportions, and the inevitable rediscovery of already­ recognized proof in regards to the enzyme. Scientists are taught early of their careers that, within the phrases of Sir John Herschel, "Hasty generalization is the bane of technology. " however, moments arrive in all spheres of medical job while generalization turns into crucial, to codify and to choose from the mass of knowledge already accrued, and to supply beginning issues for brand spanking new advancements and new strains of research. this is often very true in a box akin to alkaline phosphatase study, during which very genuine risks exist that the seeds of basic knowing could be misplaced amidst an unexamined harvest of empirical observations. The background of the research of alkaline phosphatase presents numerous cases while useful generalizations have emerged. sometimes, the conclusions drawn at the foundation of accessible proof have been improper; extra usually, they've got stood the try out of extra experimentation, and regularly, they've got supplied new insights into the character and correct­ ties of this enzyme.

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Extra resources for Alkaline Phosphatase

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Distribution of acid phosphatase in the tissues under normal and under pathological conditions, Arch. , 32,189,1941. 193. , Calcification and phosphatase, Am. J. , 19, 197, 1943. 194. , Histochemical specificity of phosphatase, Proc. Soc. Exp. Bioi. , 70,7,1949. 195. , Sources of error in enzymatic histochemistry,J. Lab. Clin. , 35,802,1950. 196. , Alkaline phosphatase of cell nuclei, J. Lab. Clin. , 37, 526, 1951. 197. , La recherche histochimique des phosphatases: Etude critique, Bull. Histol.

Studies on the phosphatase. The influence of some electrolytes on the phosphatases of animal tissues: Phosphatases of the liver, kidney, serum and bones of the rabbit, Biochem. , 29, 517, 1935. 135. , Glycerophosphatspaltung durch Nierenphosphatase und ihre Aktivierung, Z. Physiol. , 172, 182,1927. 136. , Uber Nierenphosphatase und ihre Aktivierung, Z. , 177, 211, 1928. 137. Jenner, H. , and Kay, H. , The phosphatases of mammalian tissues. III. Magnesium and the phosphatase system,1. Bioi. , 93, 733,1931.

23. , Uber das Vorkommen einer Glycerophosphotase in tierischen Organen, Biochem. , 39,1,1912. 24. , Verhalten der Kohlenhydratphosphosiiure Ester im Tierk6rper, Z. Physiol. , 79, 375, 1912. 25. Schmidt, R, Weitere Untersuchungen tiber Fermente in Darminhalt (Meconium) und Mageninhalt menschiicher Foeten und Neugeborener, Biochem. , 63, 287, 1914. 26. , Versuche tiber Vorkommen und Wirkung der Saccharophosphatase im Pflanzenorganismus, Biochem. , 119, 73, 1921. 27. , Zur Kenntnis der Phosphatasen.

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Alkaline Phosphatase by Robert B. McComb

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