Download e-book for kindle: A Handbook of Applied Statistics in Pharmacology by Katsumi Kobayashi

By Katsumi Kobayashi

ISBN-10: 157808752X

ISBN-13: 9781578087525

Statistics performs a massive function in pharmacology and similar matters resembling toxicology and drug discovery and improvement. fallacious statistical device choice for reading the information acquired from reports can result in wrongful interpretation of the functionality or security of gear. This publication communicates statistical instruments in basic language. The examples used are just like those who scientists come across usually of their examine quarter. The authors offer cognitive clues for number of acceptable instruments to research the information received from the experiences and clarify tips to interpret the results of the statistical research.

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Extra info for A Handbook of Applied Statistics in Pharmacology

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J. Am. Stat. , 62, 399–402. E. D. (2004): Designing Experiments and Analysing Data—A Model Comparison Perspective. , New Jersey, USA. , Kitazawa, T. , Ohishi, T. and Edamoto, H. (2009): Carbon tetrachloride-induced hepatotoxicity in pregnant and lactating rats. J. Toxicol. , 34(2), 175–181. Nichols, D. G. (1979): A general ANOVA method for robust test of additive models for variance. J. American Stat. , 74, 877–880. G. (1981): A simple test for variance effects in experimental designs. Psych. , 89, 570–574.

Exp. , 64(1), 71–78. W. (1998). Invalidation of parametric and nonparametric statistical tests by concurrent violation of two assumptions. J. Exp. , 67(1), 55–68. 7 Tests for Significant Differences Null Hypothesis The main objective of conducting an animal experiment is to know whether the treatment with a test item causes any effect compared to the control group. The comparison between the treatment group/s and the control group is made using various statistical tools. The selection of an appropriate statistical tool is based on certain assumptions.

ICH Topic E 9—Statistical Principles for Clinical Trials, CPMP/ICH/363/96, London, UK. J. (1995): Thoughts suggested by a recent paper: Questions on non-parametric analysis of quantitative data (letter to editor). J. Toxicol. , 20(2), 165–170. L. Y. (1994): A six-month interperitoneal repeated dose toxicity study of tazobactam/piperacillin and tazobactam in rats. J. Toxicol. , 19, Suppl. II, 155–176. Analysis of Normality and Homogeneity of Variance 35 Hollander, M. A. (1973): Nonparametric Statistical Methods, John Wiley and Sons, New York, USA.

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A Handbook of Applied Statistics in Pharmacology by Katsumi Kobayashi


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